Genetic Disorders

CSNB

Congenital night blindness (Congenital Stationary Night Blindness) is a hereditary eye disease found in Briards (Berger de Brie) with a mutation in the RPE65 gene identified as underlying cause.

Due to its autosomal recessive inheritance only dogs carrying two copies of the mutated RPE65 gene are affected while carriers of this disorder (animals carrying one copy of the mutation) remain clinically normal. Since ophthalmic examination alone is unable to distinguish carriers from non-carriers, genetic testing is needed for taking an animal’s PRE65 status into consideration for breeding purposes.

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Genetic Disorders
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